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Test ID TOXO Toxoplasma Immunostain, Technical Component Only


Ordering Guidance


This test includes only technical performance of the stain (no pathologist interpretation is performed). If diagnostic consultation by a pathologist is required order PATHC / Pathology Consultation.



Shipping Instructions


Attach the green pathology address label and the pink Immunostain Technical Only label included in the kit to the outside of the transport container.



Specimen Required


Supplies: Immunostain Technical Only Envelope (T693)

Specimen Type: Tissue

Container/Tube: Immunostain Technical Only Envelope

Preferred: 2 Unstained positively charged glass slide (25- x 75- x 1-mm) per test ordered; sections 4-microns thick.

Acceptable: Formalin-fixed, paraffin-embedded (FFPE) tissue block


Useful For

Identification of Toxoplasma gondii infection

Reflex Tests

Test ID Reporting Name Available Separately Always Performed
IHTOI IHC Initial, Tech Only No No
IHTOA IHC Additional, Tech Only No No

Method Name

Immunohistochemistry (IHC)

Reporting Name

Toxoplasma IHC, Tech Only

Specimen Type

TECHONLY

Specimen Stability Information

Specimen Type Temperature Time Special Container
TECHONLY Ambient (preferred)
  Refrigerated 

Clinical Information

Immunohistochemical staining for Toxoplasma gondii can help identify the organisms in the cytoplasm of infected cells. T gondii is a sporozoan that lives as an intracellular parasite in various tissues of vertebrates. T gondii is transmitted via raw or undercooked meat, contaminated soil, or by direct contact. Pregnant women and immunosuppressed patients are at highest risk for infection.

Interpretation

This test does not include pathologist interpretation; only technical performance of the stain is performed. If an interpretation is required, order PATHC / Pathology Consultation for a full diagnostic evaluation or second opinion of the case.

 

The positive and negative controls are verified as showing appropriate immunoreactivity and documentation is retained at Mayo Clinic Rochester. If a control tissue is not included on the slide, a scanned image of the relevant quality control tissue is available upon request, call 855-516-8404.

 

Interpretation of this test should be performed in the context of the patient's clinical history and other diagnostic tests by a qualified pathologist.

Clinical Reference

1. Mostafa NES, Abdel Hamed EF, Rashed HES, Mohamed SY, Abdelgawad MS, Elasbali AM: The relationship between toxoplasmosis and different types of human tumors. J Infect Dev Ctries. 2018 Feb 28;12(2):137-141

2. Arnold SJ, Kinney MC, McCormick MS, Dummer S, Scott MA: Disseminated toxoplasmosis. Unusual presentations in the immunocompromised host. Arch Pathol Lab Med. 1997;121(8):869-873

3. Held TK, Kruger D, Switala AR, et al: Diagnosis of toxoplasmosis in bone marrow transplant recipients: comparison of PCR-based results and immunohistochemistry. Bone Marrow Transplant. 2000;25(12):1257-1262

Day(s) Performed

Monday through Friday

Report Available

1 to 3 days

Test Classification

This test has been cleared, approved, or is exempt by the US Food and Drug Administration and is used per manufacturer's instructions. Performance characteristics were verified by Mayo Clinic in a manner consistent with CLIA requirements.

CPT Code Information

88342-TC, primary

88341-TC, if additional IHC

LOINC Code Information

Test ID Test Order Name Order LOINC Value
TOXO Toxoplasma IHC, Tech Only Order only;no result

 

Result ID Test Result Name Result LOINC Value
70881 Toxoplasma IHC, Tech Only Bill only; no result

Forms

If not ordering electronically, complete, print, and send a Immunohistochemical (IHC)/In Situ Hybridization (ISH) Stains Request (T763) with the specimen.

Mayo Clinic Laboratories | IHC Catalog Additional Information:

mcl-ihc